Using the PS 250 Homogenizer

I received several 10ml flavors so I thought this would be a good opportunity to show the equipment in use. However, what is occurring is not visible to the eye and occurring at the 2 to 5 micron level. The animation I posted on the other thread is useful to demonstrate the process and far better than I could ever explain it.

I start mixing in whatever size bottle I want to make. While I have a hotplate/stirrer, I am not using it. Instead I use a tiny crock pot and put my bottles in and heat to 140F/60C. It stays at that temp.

While these devices are called hand held, they really are not. They should be mounted on a stand. I made this stand holder so I could set the height and lift it to place the homogenizer shaft in the bottle, and also lift it out for cleaning. (More below) It works very well and is simple.

This is the Pro Scientific model 250. 3/4 Hp 10-30 K RPM. I’ve found that the optimum speed for juice making is around 15K. Any faster and it will produce air bubbles and the product manual warns against this. They are designed to minimize or eliminate aeration. This is the machine mounted on the stand with a 7mm size generator.

For mixing in bottles with the 7mm, I simply cut the rubber bulb off a bottle cap and slip it onto the shaft. Similarly, when using my 10 ml generator I use a rubber flask stopper that I drilled a 10 mm hole in and tapered it to fit and seal a bottle. Whether this is necessary for juice making is questionable, but the companies making these offer similar products. In fact, most homogenizers of this size are used in test or centrifuge tubes. These simply slip on. I would rather have this than have one of my ‘juice mooch’ friends walk in and sneeze or something.

I run the homogenizer for about one minute though half of that is likely enough in small bottles. The manufacturer explains that after all materials have been run through the generator nothing will be accomplished by longer times. The shear effect (particle reduction) is very small.


The manufacturer recommends that the generator be ran in a solvent between uses and that is how I use it. I keep a drinking glass with hot tap water with one drop of dish-washing detergent and another glass of distilled water. I simply lift the homogenizer and run it for 30 second or so in each. I have disassembled the generator and literally licked the parts. No taste whatsoever. By using distilled water to rinse, any residue will mix and not introduce anything unwanted. I disassemble and clean after my mixing session.

I made 7 testers in a little over an hour including heating, cool down, and adding nic while now using an ultrasonic cleaner for this final step. They are completely vape ready.


That is pretty damn cool


Hella cool, and I’ll add “I wish I lived close to you @Guitarded!”

Totally respect the contributions, and appreciate your sharing your thoughts and ideas. It’s been wonderful food for thought, as well as quite enjoyable to read!

I wish I had the funds to get into this level of “toys”… But I’m glad I don’t OTOH. My personal rabbit hole is already amply deep thank you very much! =P lol


Thanks you guys. I’m enjoying this immensely and hope I’m not boring the shit out of everyone or coming off as some know it all prick. I sure don’t and the day I quit trying to learn things will be the day they put me under.

It would be nice to be in the same location, but OTOH here we have a group conversation with people scattered across the globe. That’s pretty incredible to this old man.

And you know the “rule”- he who dies with the most toys “wins.” :thinking::grin:


Just because we don’t all post on the Homogenizer threads doesn’t mean we don’t read and adsorb all the gems of valuable info your generating
Do keep em coming.


After re reading these posts I saw I needed to update. In the small bottles I use the 7 mm generator at 15-20K RPM. For larger quantities I use the 10 mm generator up to full speed of 30 K. It is important to start slow and gradually increase the speed which starts a circular downflow and pulls the liquid into the rotor/stator. A powerful suction is developed and the liquid is sheared and expelled by intense force. I’ve noticed elsewhere that people tend to think these are stirrers. They are not. They pull the liquids in and literally slam everything together.

Industrial Batch Mixers | Batch Mixer


Geez do I hate missing awesome threads. This is one of them. That is, as Sparky said, hella cool!!


I agree, this stuff is truly fascinating. I would imagine this is a peek behind the curtain into how some better premium commercial juice is made too…


So I’m curious about flavors like cap sugar cookie that tend to fade over a traditional month or more steep…does this flavor fade from traditional steeping carry over, or does combining the flavors thoroughly while still freshly mixed negate that? Lemon is another flavor that seems to fade out of mixes as well…


IME, it varies. And I can only attribute the variance to the innate properties of particular flavors. I’m not sure if it’s inherent in the chemical composition, the process in which they’re created, or some combination thereof.

Take Cap lemon meringue pie for instance. That one fades with time regardless of whether I’ve just put it away, or run it through the USC first.

While on the other hand, MF lemon gets stronger with time. But it’s processed differently, and is also an extract.

I have Ina lemon… But my batch was suspect since it had to be used at almost 5% to start with. So I can’t even hazard a guess on that due to the uncertainties. (it fades slightly, but not nearly as bad as Cap and some others.)

Note: all times above are based on tests up to 4 and 6 weeks.

PS: I’m long overdue on using Sugar Cookie since I last did, so I won’t even try to remember. :laughing:


So it might be worth adding those flavours later? Or does that just destroy the initial intent?


Just that statement alone shows just how much there is that goes into mixing.

Baking a cake is so easy. Measure the right amounts, wet team first, dry team second, combine, bake. If only DIY ejuice was that simple. But no… You have to homogenize. You have to heat. Or you have to shelve it for weeks. You can’t add the nic right away if you are using mech steeping (starting to hate the word ‘steeping’ by the way). You have to figure out not only proper %, but also which vendor version works best. You have to learn what PG / VG ratio works best for you. You have to- and so on.

My wife knows I make all our juices. But she has ZERO idea how much effort I put in to it. I simply go to my “lab”, and product emerges. Must be nice!!!


I think it safe to say that anyone can find a broad consensus that “steeping” is very bad term that somehow “stuck” in the ejuice making world when in fact we are not “steeping” anything. We are not making extracts or tinctures and there are no solids we are dealing with. We are attempting to mix chemicals into a homogeneous state. In @anon96380778 Sous Vide thread (ongoing) he posed the questions of whether this was physical or chemical change. I answered that it is both. We all use the term steep but I cringe every time I use it. Personally I think “maturation” would work better and indeed I have found this term used in peer reviewed studies of processing methods and equipment, particularly for modern day wine making using ultrasonic sonicator equipment.

Even the term homogenize seems to be problematic concerning ejuice making. I my first posts about this Homogenizing Equipment Used for E-liquid Making I tried to clarify:
“The word homogenize means “to make or render homogeneous” while homogeneous means the same composition, structure or character throughout”. Homogenizing is an umbrella term - a word which covers a very large area. When someone says that they are homogenizing, they may mean that they are actually doing one or more of the following; blending, mixing, (cell) disrupting, emulsifying, dispersing, stirring etc.”

What we are dealing with in this thread is homogenization with a high shear rotor stator mixer. While the DIY community is understandably unfamiliar these they have been in use for decades universally across food, beverage, cosmetic, pharmaceutical, chemical, and lubricant industries.

Yes, combining the flavors thoroughly negates this providing you adhere to certain do’s and don’ts. After all, what the long steep is attempting to accomplish, despite the claims of “magic” is to “render the mix homogeneous.” See above.

There are many causes for flavor fade and we are dealing with thousands of differing chemical compositions. Assigning a universal steep time factor to a brand or line of chemicals is to me absurd. My thoughts on all of this are in the recent Sous Vide thread in which I emphasize that while high shear mixing is far superior to conventional agitation methods, it is not the only way to achieve this. I also deal with and quoted ab nauseum recent statements made by Flavorah which mirror mine concerning oxidation and mix stability over time. In essence, one major cause of flavor change and loss is oxidation.


Ah, but you see… when my children were young I was able to make things disappear and re-appear all the time. I was able to detach their nose. I was able to remove my finger and put it back on. Magic, it seems, is in the mind of the beholder. And in the DIY mixing community, those that choose to continue to believe that unknown forces are at work converting a host of disparate agents into a single, smooth blend, and it happens only through time, are indeed believers of “magic”, as that is exactly what is happening in their eyes. Poof and abracadabra and shit like that. “Wow, I tried it a month later and it was awesome, like magic!!!”

We choose to see past the mythical wonder and view this through the lens of science. For me personally, looking at it not as a recipe of flavors but as a chemical blending process lifts the veil and makes it very understandable. It is, after all, all but completely the same thing as manufacturing hand lotion, or cola, or ‘fill in the blank’, etc. It is the blending of chemicals designed to create a product. As you said, it happens all the time and has been for years in the food and personal care industry, and in fact basically all industries. If we can achieve maturation through mechanical means and eliminate the time factor, why would we not? :sunglasses:


It very well could be.
I don’t think it would destroy the intent, but I do think it would be reflected in how well it “disperses” in the vape experience itself (due to not being as well integrated into the VG).
Meaning: there could be variances from one draw to the next of how much lemon is perceived.

It could be detrimental depending on how complex the recipe is, or how subtle any accompanying flavors could be. Hard to generalize.

Personally, my answer to the problem (flavor fade) has been to try and make no more than I’ll use in the target window. IE: if it’s only good between weeks 2 and 3, then I don’t make more than about 30ml.


Excellent solution. When I encounter a flavor that fades to black really quickly, I just don’t use it There are so many flavors and so many recipes to choose from that I would just find a different one. But making it in small quantities is a really smart thought.


Even though I buy 250ml bottles of one shot I steep it at 70/30 then pour 60ml (50ml w/10ml nic shot) at a time for the same reasons